THE GROWING CRAZE ABOUT THE FIBRILLAR ABSORBABLE HEMOSTAT

The Growing Craze About the Fibrillar Absorbable Hemostat

The Growing Craze About the Fibrillar Absorbable Hemostat

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Fibrillar Absorbable Hemostat: A Promising Aid for Bleeding Control in Colorectal Tumors


Colorectal cancer, one of the most widespread cancers worldwide, often requires sophisticated treatment modalities to attain optimum results. Among these, endoscopic submucosal dissection (ESD) has become an appealing method for the early-stage management of colorectal tumors. However, the procedure's success can be tempered by postoperative issues such as postponed bleeding and perforation, in addition to the challenge of handling large mucosal defects. Moreover, direct exposure to gastrointestinal flora increases the risk of bacteremia and endotoxemia. In the quest for safer and more reliable services, researchers and clinicians are continuously exploring alternative techniques. Fibrillar absorbable hemostat such as Surgicel ® Fibrillar ™ (Ethicon), nevertheless, emerges as a game-changer provides a multifaceted approach to post-ESD care, supplying both hemostatic support and localized bactericidal results.

A noteworthy item in this realm is Surgi-ORC ® Fibril from Aegis Lifesciences, including the following key qualities:

Key Features of Surgi-ORC ® Fibril:

• Lightweight, tufted, soft and layered structure
• Provides high versatility and conformability to surgical sites
• Suitable for irregular shaped wounds and hard-to-reach areas
• Bactericidal properties
• Soft, layered product conforms and "melts in" to bleeding tissue
• Completely absorbable
• 7 layers fibrillose fabric
• Designed for hemostasis in

How does Surgi-ORC ® Fibril Work?
Surgi-ORC ® Fibrilis made up of oxidized regenerated cellulose, which, upon contact with blood, swells into a gelatinous mass, aiding in embolisms development and preventing more bleeding. Moreover, its low pH of 3.4 exhibitions powerful bactericidal properties, minimizing the risk of infection significantly.

Clinical Study Results:

A clinical study was performed at the University of Soonchunhyang Hospital in Bucheon, Korea, sheds light on the effectiveness of Surgicel ® Fibrillar ™ in colorectal ESD. In a cohort of 49 patients, Surgicel ® Fibrillar ™ was effectively applied to cover the whole mucosal defect following ESD, without any Surgicel-related problems. Extremely, none of the patients in the Surgicel group experienced postponed bleeding or perforation, Fibrillar Absorbable Topical Hemostat marking a substantial improvement over traditional ESD strategies. Moreover, Surgicel ® Fibrillar ™ was connected with much shorter hospital stays and lower inflammatory markers, suggesting quicker healing and enhanced postoperative results.

Fig. 1: A) Lateral spreading tumor; B) Dissected colon LST by colon endoscopic submucosal dissection.; C) Surgicel was positioned onto the mucosal defect to cover the entire mucosal defect; D) Surgicel swelled into a gelatinous mass [1]

Conclusion:

In the realm of colorectal cancer treatment, every advancement brings us closer to our ultimate goal: improving patient outcomes and improving lifestyle. Fibrillar absorbable hemostat represents a critical turning point in this journey, using a powerful mix of hemostatic effectiveness and antimicrobial defense. As we continue to press the borders of development, let us accept the transformative capacity of Fibrillar absorbable hemostat and embark on a path towards much safer, more efficient colorectal endoscopic resection.

Referrals:

[1] Myung YS, Ko BM, Han JP, Hong SJ, Jeon SR, Kim JO, Moon JH, Lee MS. Effectiveness of Surgicel® (Fibrillar) in patients with colorectal endoscopic submucosal dissection. Surgical endoscopy. 2016 Apr;30:1534-41. DOI:10.1007/s00464-015-4369-5


Article Tags: Fibrillar Absorbable Hemostat, Fibrillar Absorbable Topical Hemostat.

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